Interactions of Dietary Whole-Grain Intake With Fasting Glucose– and Insulin-Related Genetic Loci in Individuals of European Descent A meta-analysis of 14 cohort studies

نویسندگان

  • JENNIFER A. NETTLETON
  • NICOLA M. MCKEOWN
  • ROZENN N. LEMAITRE
  • MARY K. WOJCZYNSKI
چکیده

OBJECTIVE — Whole-grain foods are touted for multiple health benefits, including enhancing insulin sensitivity and reducing type 2 diabetes risk. Recent genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) associated with fasting glucose and insulin concentrations in individuals free of diabetes. We tested the hypothesis that whole-grain food intake and genetic variation interact to influence concentrations of fasting glucose and insulin.

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Interactions of Dietary Whole-Grain Intake With Fasting Glucose– and Insulin-Related Genetic Loci in Individuals of European Descent

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تاریخ انتشار 2010